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Peptide-engrafted liposomes : effective delivery vehicles for antigen and DNA to modulate immunity

Abdus Salam, Faham

Description

Since dendritic cells (DC) possess the unique ability to prime na{u00EF}ve T cells and orchestrate subsequent antigen (Ag)-specific effector functions, a new generation of cancer therapies is emerging, which seek to restore host defence by triggering DCs to generate anti-tumour immunity. Currently, a wide range of nanoparticle-based vaccines are being developed to harness the immune system to recognize and eradicate cancer cells. However, the search for an effective, versatile and 'easy to...[Show more]

CollectionsOpen Access Theses
Type: Thesis (PhD)
URI: http://hdl.handle.net/1885/151622

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