Post-transcriptional control of T follicular helper cells
Antibody production is a key feature of the adaptive immune response. High affinity antibodies neutralise and clear invading pathogens, thereby protecting the host against microbial infections. It is now well-established that T follicular helper (Tfh) cells – a distinct subset of CD4+ T helper cells – are essential in providing cognate help to B cells in the germinal centre (GC) to differentiate into memory and long-lived plasma cells that secrete high affinity antibodies. However,...[Show more]
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