Skip navigation
Skip navigation

Consequences of oncogenic CARD11 signalling for B cells

Jeelall, Yogesh


Diffuse large B cell lymphoma is the most common form of Non Hodgkin’s lymphoma, accounting for forty percent of cases. Gain of function CARD11 mutations have been found in approximately thirteen percent of DLBCL patients. CARD11 functions as a scaffold protein and relays signals from the antigen receptor to the JNK and NFkB signaling pathways, which contribute to the survival, proliferation and differentiation of lymphocytes. The consequences of acquiring...[Show more]

CollectionsOpen Access Theses
Date published: 2015
Type: Thesis (PhD)
DOI: 10.25911/5d7635304f0a7


File Description SizeFormat Image
Jeelall Thesis 2016.pdf10.72 MBAdobe PDFThumbnail

Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  19 May 2020/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator