Structure, function and evolution of flavin/deazaflavin dependent oxidoreductases (FDORs) in mycobacteria
Mycobacterium tuberculosis, the causative agent of Tuberculosis (TB), is notorious for its ability to persist during infection and evade the host immune response, although the cellular mechanisms behind this are not yet fully understood. Like other mycobacteria, M. tuberculosis produces the cofactor F420 found in Actinobacteria and Archaea, which is important, through unknown mechanisms, for its survival during oxidative stress and in the reactivation of...[Show more]
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