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Protein-Ligand Interactions by NMR and EPR Spectroscopy

Abdelkader Ali, Elwy Hassan


Pulse electron paramagnetic resonance (EPR) distance measurements using double electron-electron resonance (DEER) experiments have been established as a powerful tool in structural biology. DEER experiments have the ability to measure the distance between two paramagnetic centres in biological macromolecules in the range of about 2 to 8 nm. The paramagnetic centres are usually introduced into proteins by site-directed spin labelling (SDSL) of cysteine ...[Show more]

CollectionsOpen Access Theses
Date published: 2016
Type: Thesis (PhD)


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