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Understanding the interaction between RNA-directed DNA methylation and DNA demethylases and its role in Fusarium oxysporum disease response in Arabidopsis thaliana

Lee, Joanne

Description

RNA-directed DNA methylation (RdDM), directed by 24 nt small interfering RNA (siRNA), is a plant-specific de novo cytosine methylation pathway responsible for natural suppression of repeat sequences such as transposons and centromeric repeats. RdDM can be counteracted by DNA demethylation, which in Arabidopsis is catalyzed by four DNA demethylases; Demeter (DME), Repressor of silencing (ROS1) and Demeter-like 2 and 3 (DML2, DML3). Early studies...[Show more]

CollectionsOpen Access Theses
Date published: 2016-01
Type: Thesis (PhD)
URI: http://hdl.handle.net/1885/107170

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