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Wnt responsive SUMOylation regulates ZIC protein activity to promote murine neural crest specification

Bellchambers, Helen

Description

Neural crest cells are a transient population of multipotent cells which arise at the border of the neural and non-neural ectoderm (known as the neural plate border) during neurulation. These cells migrate through the embryo and differentiate into a range of cell types so diverse that the neural crest is sometimes termed the fourth germ layer. Neural crest cell formation and differentiation is driven by a cascade of transcription factor activity at the neural...[Show more]

CollectionsOpen Access Theses
Date published: 2015-06
Type: Thesis (PhD)
URI: http://hdl.handle.net/1885/101779

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