Wnt responsive SUMOylation regulates ZIC protein activity to promote murine neural crest specification
Neural crest cells are a transient population of multipotent cells which arise at the border of the neural and non-neural ectoderm (known as the neural plate border) during neurulation. These cells migrate through the embryo and differentiate into a range of cell types so diverse that the neural crest is sometimes termed the fourth germ layer. Neural crest cell formation and differentiation is driven by a cascade of transcription factor activity at the neural...[Show more]
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