Induction of HO-1 in tissue macrophages and monocytes in fatal falciparum malaria and sepsis
BACKGROUND As well as being inducible by haem, haemoxygenase -1 (HO-1) is also induced by interleukin-10 and an anti-inflammatory prostaglandin, 15d PGJ2, the carbon monoxide thus produced mediating the anti-inflammatory effects of these molecules. The cellular distribution of HO-1, by immunohistochemistry, in brain, lung and liver in fatal falciparum malaria, and in sepsis, is reported. METHODS Wax sections were stained, at a 1:1000 dilution of primary antibody, for HO-1 in tissues...[Show more]
|Collections||ANU Research Publications|
|Clark_Induction2003.pdf||837.22 kB||Adobe PDF|
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.