Skip navigation
Skip navigation

Induction of HO-1 in tissue macrophages and monocytes in fatal falciparum malaria and sepsis

Clark, Ian; Awburn, Melissa; Hardy, Brigid; Liomba, George; Molyneux, Malcolm


BACKGROUND As well as being inducible by haem, haemoxygenase -1 (HO-1) is also induced by interleukin-10 and an anti-inflammatory prostaglandin, 15d PGJ2, the carbon monoxide thus produced mediating the anti-inflammatory effects of these molecules. The cellular distribution of HO-1, by immunohistochemistry, in brain, lung and liver in fatal falciparum malaria, and in sepsis, is reported. METHODS Wax sections were stained, at a 1:1000 dilution of primary antibody, for HO-1 in tissues...[Show more]

CollectionsANU Research Publications
Date published: 2003-11-19
Type: Journal article
Source: Malaria Journal
DOI: 10.1186/1475-2875-2-41


File Description SizeFormat Image
Clark_Induction2003.pdf837.22 kBAdobe PDFThumbnail

Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  20 July 2017/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator