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Neutral amino acid transport in epithelial cells and its malfunction in Hartnup disorder

Broer, Stefan; Cavanaugh, Juleen; Rasko, John Edward

Description

Hartnup disorder is an autosomal recessive abnormality of renal and gastrointestinal neutral amino acid transport. A corresponding transport activity has been characterized in kidney and intestinal cells and named system B0. The failure to resorb amino acids in this disorder is thought to be compensated by a protein-rich diet. However, in combination with a poor diet and other factors, more severe symptoms can develop in Hartnup patients, including a photosensitive pellagra-like skin rash,...[Show more]

CollectionsANU Research Publications
Date published: 2005
Type: Journal article
URI: http://hdl.handle.net/1885/82350
Source: Biochemical Society Transactions
DOI: 10.1042/BST0330233

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