Identification, Characterization and Crystal Structure of the Omega Class Glutathione Transferases

Board, PhilipCoggan, MarjorieChelvanayagam, GarethEasteal, SimonJermiin, Lars SommerSchulte, JurgenDanley, DHoth, LGriffor, MKamath, ARosner, MChrunyk, BPerregaux, DGabel, CGatens, MoiraPandit, J2015-12-130021-9258http://hdl.handle.net/1885/90398A new class of glutathione transferases has been discovered by analysis of the expressed sequence tag data base and sequence alignment. Glutathione S-transferases (GSTs) of the new class, named Omega, exist in several mammalian species and CaenorhabditisKeywords: glutathione; glutathione transferase; glutathione transferase omega 1 1; unclassified drug; amino acid sequence; article; disulfide bond; DNA sequence; enzyme activity; enzyme analysis; enzyme localization; enzyme structure; expressed sequence tag; nucleoIdentification, Characterization and Crystal Structure of the Omega Class Glutathione Transferases200010.1074/jbc.M0017062002015-12-12