Aminocyclodextrins to facilitate the deprotonation of 4- tert -butyl-α-nitrotoluene

Barr, LornaEaston, ChristopherLee, KittyLincoln, Stephen F2015-12-131477-0520http://hdl.handle.net/1885/819906A-Amino-6A-deoxy-β-cyclodextrin enhances the rate of the deprotonation of 4-terf-butyl-α-nitrotoluene. The rate constants for reaction of the cyclodextrin-bound species, kinc = 4 × 10-3, 9 × 10-3 and 19 × 10 -3 s-1, at pH 6.0, 6.5 and 7.0, respectivKeywords: Acceleration; Amines; Complexation; Deuterium; Ketones; Oligomers; pH effects; Toluene; 4-terf-butyl-?-nitrotoluene; Aminocyclodextrins; Hydrogen-deuterium exchange; Rate acceleration; Reaction kinetics; cyclodextrin; drug derivative; toluene; article; chAminocyclodextrins to facilitate the deprotonation of 4- tert -butyl-α-nitrotoluene200510.1039/b506187c2015-12-11