Morris, KellyCao, Feihua (Lucy)Onagi, HidekiAltamore, TimothyGamble, AllanEaston, Christopher2015-12-100960-894Xhttp://hdl.handle.net/1885/69230The interactions of nineteen peptide substrates and fifteen analogous peptidomimetic glycolate inhibitors with human peptidylglycine α-amidating monooxygenase (PAM) have been investigated. The substrates and inhibitors are the prohormones of calcitonin aKeywords: alpha amidating enzyme; antineoplastic agent; calcitonin; enzyme inhibitor; glycolic acid; oxytocin; peptidomimetic glycolate inhibitor; peptidylglycine alpha amidating monooxygenase inhibitor; unclassified drug; amino acid sequence; antineoplastic activi Glycolate inhibitors; Human cancer; Peptide substrates; Peptidylglycine a-amidating monooxygenase; ProhormonesProhormone-substrate peptide sequence recognition by peptidylglycine α-amidating monooxygenase and its reflection in increased glycolate inhibitor potency201210.1016/j.bmcl.2012.10.0042016-02-24