Lack of Association of a Single-Nucleotide Polymorphism of the mu-Opioid Receptor Gene With Anxiety-Related Traits: Results From a Cross-Sectional Study of Adults and a Longitudinal Study of Children

Jorm, Anthony FPrior, M HSanson, Ann VeronicaSmart, DianaZhang, YafeiTan Ying Feng, SebrinaEasteal, Simon2015-12-132015-12-131552-4825http://hdl.handle.net/1885/92163There is evidence from animal experiments that the μ- and δ-opioid receptors may play a role in anxiety and depression. It might therefore be expected that functional polymorphisms of these genes in humans are associated with anxiety and depression. WeKeywords: asparagine; aspartic acid; delta opiate receptor; mu opiate receptor; mu opiate receptor; adolescent; adult; anxiety; article; behavior disorder; child; child development; community care; depression; genetic association; genetic polymorphism; health surve µ-opioid receptor gene; Anxiety; Depression; OPRM1; Personality; TemperamentLack of Association of a Single-Nucleotide Polymorphism of the mu-Opioid Receptor Gene With Anxiety-Related Traits: Results From a Cross-Sectional Study of Adults and a Longitudinal Study of Children200210.1002/ajmg.106432015-12-12