Chu, JessieHong, Nancy AMasuda, Claudio A.Jenkins, Brian V.Nelms, KeatsGoodnow, ChristopherGlynne, RichardWu, HuaMasliah, EliezerJoazeiro, Claudio A.P.Kay, Steve A.2015-12-080027-8424http://hdl.handle.net/1885/33945A mouse neurological mutant, lister, was identified through a genome-wide N-ethyl-N-nitrosourea (ENU) mutagenesis screen. Homozygous lister mice exhibit profound early-onset and progressive neurological and motor dysfunction. lister encodes a RING fingerKeywords: protein listerin; ubiquitin protein ligase E3; unclassified drug; animal experiment; animal model; animal tissue; article; controlled study; genetic analysis; male; mouse; nerve degeneration; nonhuman; phenotypic variation; priority journal; protein analyA mouse forward genetics screen identifies LISTERIN as an E3 ubiquitin ligase involved in neurodegeneration200910.1073/pnas.08128191062016-02-24