Collignon, PeterConly, John MAndremont, AntoineMcEwen, Scott A.Aidara-Kane, Awa2019-11-261058-4838http://hdl.handle.net/1885/186643To the Editor — We agree with Cohen and Denning [1] that the large-scale use of antifungals in agriculture on crops is a potential threat to human populations, because resistant fungi that develop can be transmitted to humans [2]. We also agree that the issue of antimicrobial resistance should not be confined solely to the large-scale use of antibiotics. Overuse of antifungals (especially azole use) is an important issue. We also need to be concerned about possible large-scale use of antivirals in agriculture—for example, reports of amantidine and other anti-influenza antiviral use in poultry in China because of H5N1 outbreaks in fowl flocks [3, 4]—and then with the resultant risk of influenza strains developing resistance to antivirals if acquired by swine and/or humans.J. M. C. has received grants from Alberta Innovates-Health Solutions, personal fees and nonfinancial support from Pfizer, nonfinancial support from bioMérieux, and other support from the National Collaborating Centre for Infectious Diseases (Canada). A. A. has received personal fees from the Davoltera company (within the frame of the French law for innovation and research) and Cepheid and has received grants from the Agence Nationale pour le Recherche and from the European Union FP7 program. S. A. M. has been granted contracts from Health Canada and the Ontario Ministry of Agriculture, Food and Rural Affairs.2 pagesapplication/pdfen-AU© The Author 2017. Published by Oxford University Press for the Infectious Diseases Society of America.2017-04-0110.1093/cid/cix0612020-07-05