Christiadi, DSinger, Richard2022-02-072022-02-071753-0792http://hdl.handle.net/1885/259553Calciphylaxis has high mortality. Vitamin K deficiency is common in haemodialysis patients and may be a trigger for calciphylaxis due to its role in activating matrix Gla protein (a tissue inhibitor of calcification). We report the case of a 43-year-old female haemodialysis patient who developed calciphylaxis. Two months prior to the diagnosis she was found to have an undetectable plasma vitamin K concentration. The calciphylaxis completely resolved with vitamin K supplementation and an increase in haemodialysis frequency. She did not receive sodium thiosulphate or bisphosphonates. Supplementation of vitamin K in deficient patients may improve the outcome of this condition.application/pdfen-AU© The Author 2017. Published by Oxford University Press on behalf of ERA-EDTAhttp://creativecommons.org/ licenses/by-nc/4.0/calciphylaxismalabsorptionmatrix Gla proteinrenal dialysisvitamin K201810.1093/ckj/sfx1262020-12-13Creative Commons Attribution Non-Commercial License