Lantum, HoffmanBoard, PhilipAnders, Michael2015-12-130893-228Xhttp://hdl.handle.net/1885/73154Glutathione transferase zeta (GSTZ1-1) catalyzes the cis-trans isomerization of maleylacetoacetate and the biotransformation of a range of α-haloacids. The objective of this study was to determine the kinetics of the biotransformation of maleylacetone (MKeywords: acetic acid derivative; acetone; chlorofluoroacetic acid; deoxycorticosterone acetate; enzyme variant; glutathione transferase; haloacid; maleylacetoacetate; maleylacetone; meta tyrosine; unclassified drug; amino acid metabolism; article; biotransformatio200210.1021/tx010095y2015-12-11