Hendry, IanKelleher, KimBartlett, SelenaLeck, Kwong-JooReynolds, AnnaHeydon, KatharinaMellick, AMegirian, DavidMatthaei, Klaus2015-12-130006-8993http://hdl.handle.net/1885/89026Our laboratory has generated a mouse deficient in the alpha (α) subunit of the G protein, G(z), (G(zα)) gene and we have examined the involvement of G(zα) in spinal and supraspinal analgesia and tolerance mechanisms. Spinal analgesia was tested by theKeywords: delta opiate receptor; guanine nucleotide binding protein; morphine; mu opiate receptor; protein subunit; analgesia; animal experiment; animal tissue; article; controlled study; hot plate test; morphine tolerance; mouse; nonhuman; priority journal; reacti Analgesia; Behavioral testing; G protein; G(za)-deficient mice; G(z); Morphine tolerance; Opioid receptor200010.1016/S0006-8993(00)02387-82015-12-12