Clark, Ian AArnett, Simon2015-12-070165-0327http://hdl.handle.net/1885/20340Persistent and severe fatigue is a common part of the presentation of a diverse range of disease processes. There is a growing body of evidence indicating a common inflammatory pathophysiology underlying many conditions where fatigue is a primary patientKeywords: interleukin 1beta; recombinant interleukin 1 receptor blocking agent; ankylosing spondylitis; cancer fatigue; chronic fatigue syndrome; Crohn disease; depression; human; illness behavior; molecular pathology; multiple sclerosis; muscle weakness; neurasthe Biomarker; Chronic fatigue syndrome; Cytokine; Fatigue201210.1016/j.jad.2012.04.0042016-02-24