Wales, Steven MWillis, AnthonyKeller, Paul2015-12-101359-7345http://hdl.handle.net/1885/57909The first two syntheses of chiral 2,2′-biindoline are reported either in five steps from 2,2′-bioxirane, or three steps from 2,2′-biaziridine, both with exceptional enantiopurity.Keywords: 2,2' biaziridine; 2,2' biindoline; 2,2' bioxirane; amine; copper; iodide ion; palladium; silica gel; unclassified drug; addition reaction; amination; article; catalysis; chemical analysis; chemical structure; column chromatography; crystallization; enanti201010.1039/c0cc04045b2016-02-24