Verswijveren, Simone J. J. M.Lamb, Karen E.Timperio, AnnaSalmon, JoTelford, Rohan MDaly, Robin MCerin, EsterHume, ClareOlive, LisaMacKintosh, Kelly A.McNarry, Melitta A.2023-08-082023-08-081660-4601http://hdl.handle.net/1885/295299Sedentary and physical activity patterns (bouts/breaks) may be important for cardiometabolic health in early life. This study aimed to examine cross-sectional associations of total daily volume and patterns across the activity spectrum with cardiometabolic risk factors in youth aged 7–13 years. Objectively measured accelerometer and cardiometabolic risk factor data were pooled from two studies (n = 1219; 69% valid accelerometry). Total daily volume of sedentary time and light-, moderate-, and vigorous-intensity physical activity was determined. Time in sustained bouts and median bout lengths of all intensities and breaks in sedentary time were also calculated. Outcomes included body mass index, waist circumference, blood pressure, blood lipids, and a cardiometabolic summary score. Regression models revealed beneficial associations between total daily volumes of moderate- and vigorous-intensity physical activity and cardiometabolic risk. Time spent in ≥1 min vigorous-intensity physical activity bouts was beneficially associated with cardiometabolic risk, yet this disappeared after adjusting for total vigorous-intensity physical activity and confounders. Time accumulated in light- (≥1 min; ≥5 min) and moderate-intensity (≥1 min) physical activity bouts was detrimentally associated with cardiometabolic risk. Total daily volume and activity patterns may have implications for cardiometabolic risk early in life. Sporadic physical activity may be more beneficial for health than sustained physical activity.The LOOK trial received funding from The Commonwealth Education Trust and the Canberra Hospital Clinical Trials Unit. S.J.J.M.V. holds a Deakin University PhD Scholarship.L.S.O. is supported by an Alfred Deakin Postdoctoral Fellowship from Deakin Universityapplication/pdfen-AU© 2020 The authorshttp://creativecommons.org/licenses/by/4.0/physical activitysedentary behavioraccumulation patternschildadolescentcardiometabolic healthCross-sectional associations of total daily volume and activity patterns across the activity spectrum with cardiometabolic risk factors in children and adolescents202010.3390/ijerph171242862022-07-24Creative Commons Attribution licence