Altin, JosephBanwell, MartinCoghlan, PhillipEaston, ChristopherNairn, MichaelOffermann, Daniel2015-12-130004-9425http://hdl.handle.net/1885/84959A six-step reaction sequence is described for the preparation of compound 1 (NTA3-DTDA), a membrane-penetrating and potent chelator that can be incorporated into liposomes and plasma membrane vesicles containing antigens and thus allowing targeted delivery of such assemblies to a variety of cells for the purposes of eliciting anti-tumour responses. Full spectroscopic characterization of this dendritic-type compound as well as certain of its precursors is reported.Keywords: Antigens; Cells; Chelation; Dendrimers; Spectroscopic analysis; Tumors; Anti-tumour responses; Dendritic-type compound; Liposomes; Membrane-penetrating; Plasma membrane; LipidsSynthesis of NTA 3 -DTDA - A Chelator-Lipid that Promotes Stable Binding of His-Tagged Proteins to Membranes200610.1071/CH061122015-12-12