Chai, ChristinaWaring, Paul2015-12-132015-12-131351-0002http://hdl.handle.net/1885/91126Epidithiodioxopiperazines (ETPs) are a class of secondary metabolites characterized by a bridged disulfide linkage across the α,α'-positions of the dioxopiperazine ring. This class of compounds displays a range of biological activities, attributed to thKeywords: alcohol dehydrogenase; calcium ion; copper; creatine kinase; cysteine; disulfide; dithiol derivative; epidithiodioxopiperazine derivative; farnesyl trans transferase; ferric ion; gliotoxin; glutathione; hydroxyl radical; immunoglobulin enhancer binding pr20002015-12-12