Vora, TairaCorry, BenChung, Shin-Ho2015-12-100175-7571http://hdl.handle.net/1885/60940Measurements of unidirectional fluxes in ion channels provide one of the experimental methods for studying the steps involved in ion permeation in biological pores. Conventionally, the number of ions in the pore is inferred by fitting the ratio of inwardKeywords: sodium channel; article; brownian dynamic; channel gating; ion current; ion transport; molecular dynamics; Cell Membrane; Computer Simulation; Diffusion; Ion Channel Gating; Membrane Potentials; Metabolic Clearance Rate; Models, Biological; Models, Chemic Brownian dynamics; Electrophysiology; Flux ratio; Ion channel; Permeation; Sodium channel200810.1007/s00249-008-0353-52016-02-24