Kimura, TakashiPace, Suzy MWei, LanBeard, NicoleDirksen, RobertDulhunty, Angela2015-12-070264-6021http://hdl.handle.net/1885/25063The aim of the present study was to examine residues that are variably spliced in the juvenile and adult isoforms of the skeletal-muscle RyR1 (type 1 ryanodine receptor). The juvenile ASI(-) splice variant is less active than the adult ASI(+) variant andKeywords: Binding partners; Juvenile isoform; Ryanodine binding; Sarcoplasmic reticulum vesicles; Blood vessels; Muscle; Proteins; Biochemistry; binding protein; glycine; isoprotein; peptide pasi; ryanodine receptor 1; threonine; tritium; unclassified drug; alterna Alternative splicing; Inter-domain interaction; Myotonic dystrophy; Single channel recording; Skeletal ryanodine receptor; Synthetic peptide200710.1042/BJ200606862015-12-07