Shannon, M FrancesChen, XinBrettingham-Moore, Kate HHolloway, Adele F2015-12-132015-12-131573-3955http://hdl.handle.net/1885/89623T lymphocytes undergo a complex series of developmental events in the thymus to become mature but naïve circulating T cells. These naïve T cells are activated during the response to pathogens to produce immune mediators and undergo further differentiatiKeywords: beta interferon; CD4 antigen; CD8 antigen; DNA; DNA nucleotidylexotransferase; gamma interferon; granulocyte macrophage colony stimulating factor; histone; histone acetyltransferase; interleukin 2; interleukin 2 receptor alpha; interleukin 4; major histoc Chromatin; Cytokine gene; Promoter; T cell activation; T cell differentiation; Transcription200610.2174/1573395067780185872015-12-12