Martin, RowenaMarchetti, RosaCowan, AnnaHowitt, SusanBroer, StefanKirk, Kiaran2015-12-100036-8075http://hdl.handle.net/1885/52123The emergence and spread of chloroquine-resistant Plasmodium falciparum malaria parasites has been a disaster for world health. Resistance is conferred by mutations in the Chloroquine Resistance Transporter (PfCRT), an integral membrane protein localizedKeywords: amantadine; amodiaquine; artemisinin; chloroquine; piperaquine; quinine; verapamil; digestive system disorder; disease resistance; disease transmission; gene expression; health care; malaria; membrane; mutation; protein; acidity; article; binding site; co200910.1126/science.11756672016-02-24