Jorm, Anthony FChristensen, HelenHenderson, A ScottJacomb, TrishKorten, AilsaRodgers, Bryan2015-12-132015-12-130021-843Xhttp://hdl.handle.net/1885/90163In a longitudinal study of college students, B. S. Gershuny and K. J. Sher (1998) found that high neuroticism and low extraversion had a synergistic effect in predicting anxiety and depression 3 years later. This article attempted to replicate their finding using data from 2 community samples: (a) a cross-sectional survey of 2,677 persons aged 18-79 years, and (b) a longitudinal study in which 441 persons aged 70 or older were followed over 3-4 years. Both studies found that neuroticism predicted anxiety and depression, but there were no Neuroticism x Extraversion interaction effects. These results cast doubt on the generalizability of the original findings.Keywords: adult; aged; anxiety; article; cognition; depression; extraversion; female; human; individuality; longitudinal study; major clinical study; male; neurosis; personality; Adolescent; Adult; Aged; Anxiety; Australia; Cross-Sectional Studies; Depression; Extr200010.1037//0021-843X.109.1.1452015-12-12