Onagi, HidekiEaston, ChristopherLincoln, Stephen F2015-12-131523-7060http://hdl.handle.net/1885/90734(matrix presented) The pictured rotaxane is assembled in water by capping a substituted cyclodextrin composed of the wheel and axle components. The unusual dimeric structure of the rotaxane reflects the thermodynamics of the assembly process. In N,N-dimethylformamide, the corresponding monomer is the predominant product.200110.1021/ol015607e2015-12-12