Williams, CraigMander, Lewis2015-12-132015-12-131523-7060http://hdl.handle.net/1885/88379Equation presented. Rapid access to the ABCE ring system of the C 20 diterpene alkaloids was achieved by silver(I)-promoted intramolecular Friedel-Crafts arylation of a functional group-specific 5-bromo-3-azabicyclo[3.3.1]nonane derivative.Keywords: alkaloid derivative; alkane derivative; carbon; silver; article; arylation; chemical reaction; chemical structure; drug structure; drug synthesis; Friedel crafts arylation; Acylation; Alkaloids; Aza Compounds; Bridged Compounds; Bromides; Catalysis; CycliBridgehead Arylation: A Direct Route to Advanced Intermediates for the Synthesis of C-20 Diterpene Alkaloids200310.1021/ol03530602015-12-12