Wilson, Susan2015-12-100003-4800http://hdl.handle.net/1885/66552Most approaches to analysing complex genetic disorders are based on an underlying model that assumes that the probability of being affected is mainly due to the effect of a major, single disease locus. Where the penetrance (the conditional probability ofKeywords: article; controlled study; covariance; data analysis; disease predisposition; environmental factor; female; gene linkage disequilibrium; gene locus; genetic analysis; genetic disorder; genetic epistasis; genetic model; human; hypothesis; male; methodology20012015-12-10