Burns, RichardWindsor, TimButterworth, PeterAnstey, Kaarin2024-04-022024-04-022666-5603http://hdl.handle.net/1885/316445Objective Personal wellbeing reflects individuals’ experiences of positive mental health and those with high wellbeing can be described as flourishing. Increasingly, wellbeing and flourishing are informing public health policy and clinical practice. However, the long-term benefit of wellbeing and flourishing on negative mental health outcomes over the life course is not widely explored. Method Data were from the Personality and Total Health Through Life study, based in Canberra, Australia. Participants were recruited to three age cohorts (Early Adulthood n ​= ​991; Middle Adulthood n ​= ​1,510; Later Adulthood n ​= ​1,432). Wellbeing was operationalised by positive and negative affect, life satisfaction, morale, resilience and social support. Flourishing status was defined by those reporting the highest levels of wellbeing. Mental Health was operationalised by depression and anxiety symptoms, and any depressive disorder. A sub-set of early (n ​= ​439) and middle adulthood (n ​= ​1,275) participants completed the Composite International Diagnostic Interview (CIDI). Results Associations between individual wellbeing indicators with mental health were mostly attenuated or of small magnitude in multivariate analyses, except for negative affect and low mastery which consistently reported substantial 4-year risk for all age cohorts. In contrast flourishing status reported consistently strong protection against poor mental health outcomes. Conclusion Individual wellbeing indicators are not as strongly related to mental health outcomes as a higher-order latent wellbeing factor reflecting flourishing. However, multiple measures of wellbeing are needed to capture the gamut of wellbeing experiences and are related to improved mental health outcomes over the long-term and are generally consistent across adulthood.The Personality and Total Health Through Life Study was funded by the National Health and Medical Research Council (grants, 418,039, and 1002160) and parts of wave 4 by Safe Work Australia. RAB was supported by the Australian Research Council Centre of Excellence in Population Ageing Research (project #: CE110001029). KJA is funded by an Australian Research Council Laureate Fellowship # FL190100011.application/pdfen-AU© 2021 The Authors. Published by Elsevier Ltd.http://creativecommons.org/licenses/by-nc-nd/4.0/FlourishingWellbeingMental healthLifespan development202210.1016/j.ssmmh.2021.1000522022-11-13Creative Commons Attribution-NonCommercial-NoDerivatives License