Aburto, Jose ManuelCalazans, JuliaQueiroz, Bernardo LanzaLuhar, ShammiCanudas Romo, Vladimir2022-06-212022-06-212044-6055http://hdl.handle.net/1885/267423Introduction Nutrient deficiency and immune and inflammatory disturbances in early life may compromise neurodevelopment and be implicated in the aetiology of psychiatric disorders. However, current evidence is limited by its predominantly observational nature. COpenhagen Prospective Study on Neuro-PSYCHiatric Development (COPSYCH) is a research alliance between Copenhagen Prospective Studies on Asthma in Childhood (COPSAC) and Center for Clinical Intervention and Neuropsychiatric Schizophrenia Research with the overall aim to investigate effects of prenatal and early life exposures on neurodevelopment at 10 years. COPSYCH will investigate the impact of prenatal n-3 long-chain polyunsaturated fatty acids (n-3 LCPUFA) and high-dose vitamin D supplementation on neurodevelopment reflected by brain development, neurocognition and psychopathology. Moreover, the neurodevelopmental impact of early life exposures such as infections, low grade inflammation and the gut microbiome will be scrutinised.This project has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement No. 946228)application/pdfen-AU© Author(s) (or their employer(s)) 2022https://creativecommons.org/licenses/by-nc/4.0/202110.1136/bmjopen-2020-0477062021-03-07Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license