Huttley, Gavin Austin2015-12-132015-12-130737-4038http://hdl.handle.net/1885/77923The modified base 5-methylcytosine (mC) plays an important functional role in the biology of mammals as an epigenetic modification and appears to exert a striking impact on the molecular evolution of mammal genomes. The collective epigenetic functions ofKeywords: 5 methylcytosine; BRCA1 protein; dinucleotide; DNA; nucleotide; article; codon; codon substitution; CpG island; DNA methylation; DNA sequence; exon; gene mutation; mammal; maximum likelihood method; molecular evolution; molecular model; nonhuman; nucleoti BRCA1; Codon substitution model; CpG; DNA methylation; Maximum-likelihood; Molecular evolutionModeling the Impact of DNA Methylation on the Evolution of BRCA1 in Mammals200410.1093/molbev/msh1872015-12-11