Lantum, HoffmanBaggs, RaymondKrenitsky, DariaBoard, PhilipAnders, Michael2015-12-130090-9556http://hdl.handle.net/1885/91063Glutathione transferase zeta (GSTZ1-1) catalyzes the biotransformation of a range of α-haloacids, including dichloroacetic acid (DCA), and the penultimate step in the tyrosine degradation pathway. DCA is a rodent carcinogen and a common drinking water coKeywords: acetic acid; acetone; alpha haloacid derivative; carcinogen; chlorofluoroacetic acid; dichloroacetic acid; drinking water; glutathione transferase; glutathione transferase zeta; haloacid; maleylacetone; tyrosine; unclassified drug; adrenal medulla; airway200210.1124/dmd.30.6.6162015-12-12