McCarty, E JKeane, HelenQuinn, KDinsmore, W W2015-12-132015-12-130956-4624http://hdl.handle.net/1885/78841Most serological tests for syphilis rely on an individual's ability to produce antibodies. A single screening test may be unreliable for screening in those with primary immunodeficiency. We present the first reported case of primary and secondary syphilis with negative Treponema pallidum enzyme immunoassay-IgM and Venereal Disease Research Laboratory tests in a man with common variable immunodeficiency.Keywords: benzathine penicillin; immunoglobulin A; immunoglobulin G; immunoglobulin M; adult; antibody production; article; case report; common variable immunodeficiency; condyloma latum; enzyme immunoassay; homosexuality; human; immunoglobulin deficiency; maculopa Common variable immunodeficiency (CVID); Enzyme immunoassay; IgM; Syphilis; Treponema pallidum201110.1258/ijsa.2009.0094682016-02-24