N-Acetylcysteine prevents but does not reverse dexamethasone-induced hypertension

Krug, SusanneZhang, YiMori, Trevor ACroft, Kevin DVickers, JanineLangton, LeanneWhitworth, Judith2015-12-070305-1870http://hdl.handle.net/1885/234241. We have shown previously that N-acetylcysteine (NAC) prevents the increase in blood pressure induced by adrenocorticotropin treatment. The present study investigated the effect of NAC on dexamethasone (Dex)-induced hypertension. 2. Male Sprague-DawleyKeywords: acetylcysteine; dexamethasone; isoprostane derivative; nitric oxide; sodium chloride; animal experiment; animal model; article; blood pressure measurement; controlled study; drug mechanism; fluid intake; food intake; hypertension; male; metabolism; nonhum Dexamethasone; Hypertension; N-acetylcysteine; Oxidative stressN-Acetylcysteine prevents but does not reverse dexamethasone-induced hypertension200810.1111/j.1440-1681.2008.04947.x2015-12-07