Ring-Opening and -Expansion of 2,2'-Biaziridine: Access to Diverse Enantiopure Linear and Bicyclic Vicinal Diamines

Bailey, Stephen J.Wales, Steven MWillis, AnthonyKeller, Paul2015-12-101523-7060http://hdl.handle.net/1885/63610The chiral pool-derived 1,1′-ditosyl-2,2′-biaziridine has been established as a valuable building block for the divergent synthesis of enantiopure vicinal diamines. Efficient procedures for the regioselective ring opening of the biaziridine with oxygeRing-Opening and -Expansion of 2,2'-Biaziridine: Access to Diverse Enantiopure Linear and Bicyclic Vicinal Diamines201410.1021/ol502164b2015-12-10