Rhodium-catalyzed hydroformylation of 4-vinylpyridine: 4-ethylpyridine formation via an unusual cleavage of the Rh?C bond by the enolic form of the oxo product.

Lazzaroni, RaffaelloSettambolo, RobertaCaiazzo, AldoBennett, Martin2015-12-132015-12-130276-7333http://hdl.handle.net/1885/72536The hydroformylation of 4-vinylpyridine (4VP) with rhodium catalyst Rh4(CO)12 modified with phosphine ligands (PMe2Ph) is not completely chemoselective to the branched aldehyde 2-(4-pyridyl)propanal (4α), the corresponding hydrogenation product 4-ethylpyKeywords: Catalysis; Chemical bonds; Hydrogenation; Nuclear magnetic resonance spectroscopy; Rhodium compounds; Substrates; Catalyst concentration; OrganometallicsRhodium-catalyzed hydroformylation of 4-vinylpyridine: 4-ethylpyridine formation via an unusual cleavage of the Rh?C bond by the enolic form of the oxo product.200210.1021/om01053712015-12-11