A one-pot three component synthesis of b-nitro-a-amino acids and their N-alkyl derivatives

Coghlan, PhillipEaston, Christopher2015-12-132015-12-130300-922Xhttp://hdl.handle.net/1885/93747A water-based condensation of glyoxylic acid, nitroalkanes and amines is described, offering a straightforward synthesis of β-nitro-a-amino acids and their AT-alky! derivatives.A one-pot three component synthesis of b-nitro-a-amino acids and their N-alkyl derivatives19992015-12-12