Walker, AgnesButler, JamesColagiuri, Stephen2015-12-071740-2123http://hdl.handle.net/1885/20363Chronic diseases affect around 80% of older Australians, are main causes of premature death, and account for 70% of health expenditures. The novel features, building and validation of an Australian prototype model-system which simulates interventions that target several chronic diseases are described. Chronic disease progression models are linked to a population-wide microsimulation projection model that accounts for demographic, socio-economic and health characteristics, comorbidities, health expenditures, quality of life. It estimates costs vs. benefits of simulated policy interventions. The outcome is a validated person-level prototype able to simultaneously model diabetes and Cardiovascular Disease (CVD). An illustrative model application is also presented.Keywords: Cardio-vascular disease; Chronic disease; CVD; Diabetes; Microsimulation; Economic analysis; Health; Diseases Cardiovascular disease; CVD; Diabetes; Economic analysis of health policy interventions; Microsimulation modelling; Multiple chronic diseases201010.1504/IJSPM.2010.0360182016-02-24