Mahdavi, MohammadHassanzadeh-Soureshjan, RasoulSaeedi, MinaAriafard, AlirezaBabaahmadi, RasoolRanjbar, Parviz RashidiShafiee, Abbas2026-01-012026-01-012046-2069ORCID:/0000-0003-2383-6380/work/163628657https://hdl.handle.net/1885/733800804A novel series of oxopyrazino[1,2-a]indole derivatives were prepared via a two-step synthetic procedure including a Ugi-four-component reaction followed by the transition metal-free intramolecular hydroamination of Ugi adducts in the presence of KOt-Bu in DMF at room temperature. Density functional theory (DFT) calculations were also performed to elucidate the mechanistic aspects of the reaction.9enPublisher Copyright: © The Royal Society of Chemistry.2015-11-1810.1039/c5ra17056g84948672241