Cheng, RiyanPalmer, Abraham A2015-12-101943-2631http://hdl.handle.net/1885/56193We used simulations to evaluate methods for assessing statistical significance in association studies. When the statistical model appropriately accounted for relatedness among individuals, unrestricted permutation tests and a few other simulation-based meKeywords: bootstrapping; gene dropping; gene mutation; human; molecular genetics; note; priority journal; simulation; statistical model; Computer Simulation; Genetic Variation; Humans; Models, Genetic; Models, Statistical; Pedigree; Phenotype; Quantitative Trait LoA Simulation Study of Permutation, Bootstrap and Gene Dropping for Assessing Statistical Significance in the Case of Unequal Relatedness201310.1534/genetics.112.1463322016-02-24