Turner, StephenMcArthur, CraigSutherland, DuncanKim, Jee-HyeDoherty, PeterRamshaw, IanRanasinghe, Charani2015-12-070022-1767http://hdl.handle.net/1885/26293The quality of virus-specific CD8+ CTL immune responses generated by mucosal and systemic poxvinis prime-boost vaccines were evaluated in terms of T cell avidity and single-cell analysis of effector gene expression. Intranasal (I.N.) immunization regimesKeywords: cytokine; granzyme B; interleukin 4; live vaccine; messenger RNA; virus vector; adolescent; amino acid sequence; animal cell; animal experiment; article; CD8+ T lymphocyte; controlled study; cytokine production; cytotoxic T lymphocyte; female; gene expres20072015-12-07