Daveson, KathrynGrayson, M LCosgrove, S ECrowe, SHope, WMcCa, J S2024-03-129781315152110http://hdl.handle.net/1885/315939The cephamycins are often referred to as second-generation cephalosporin antibiotics, although they differ quite markedly from antibiotics such as cefuroxime or cefaclor. A primary attribute of the cephamycins is their resistance to a variety of beta-lactamase types, such as the extended-spectrum betalactamase (ESBLs) and their narrower-spectrum parents, TEM and SHV beta-lactamases. The cephamycins to be discussed in this chapter are cefotetan and cefoxitin primarily, with secondary discussion of cefmetazole and flomoxef.application/pdfen-AU© 2017 The authors201710.1201/97813151521102022-10-23