Nielsen, KatherineWatson, MichaelAdams, DavidHammarstrom, AnnaGage, PeterHill, James OCraik, David JThomas, LindaAdams, DeniseAlewood, Paul FLewis, Richard L2015-12-130021-9258http://hdl.handle.net/1885/72976μ-Conotoxins are peptide inhibitors of voltage-sensitive sodium channels (VSSCs). Synthetic forms of μ-conotoxins PIIIA and PIIIA-(2-22) were found to inhibit tetrodotoxin (TTX)-sensitive VSSC current but had little effect on TTX-resistant VSSC currentKeywords: Assays; Brain; Conformations; Electric potential; Isomerization; Muscle; Neurology; Nuclear magnetic resonance; Sodium; Radioligands; Biochemistry; conotoxin; hydroxyproline; inhibitor protein; mu conotoxin GIIIA; mu conotoxin PIIIA; radioligand; sodium cSolution Structure of mu-Conotoxin PIIIA, a Preferential Inhibitor of Persistent Tetrodotoxin-sensitive Sodium Channels200210.1074/jbc.M2016112002015-12-11