Chai, ChristinaEdwards, AlisonWilkes, BronwynWoodgate, Ruth2015-12-132015-12-130040-4020http://hdl.handle.net/1885/87671The reactivities and selectivities of 1,3-dipolar cycloaddition reactions of ylidene piperazine-2,5-diones with mesitonitrile oxide are reported. The stereoselectivities of reactions with chiral ylidene piperazine-2,5-diones can be directed by judicious choice of substituents on the N- and/or C-substituents of the piperazinedione ring.Keywords: nitrile; oxide; piperazine derivative; article; carbon nuclear magnetic resonance; chemical reaction; chirality; cycloaddition; priority journal; stereochemistry; X ray diffraction Amino acids and derivatives; Cycloadditions; Nitrile oxides; X-ray crystal structures200310.1016/j.tet.2003.09.0402015-12-12