Siepielski, Adam M.Morrissey, Michael B.Buoro, MathieuCarlson, Stephanie M.Caruso, Christina M.Clegg, Sonya M.Coulson, T.DiBattista, JosephGotanda, Kiyoko M.Francis, Clinton D.Kruuk, Loeske2019-10-150036-8075http://hdl.handle.net/1885/176969The comment by Myers-Smith and Myers focuses on three main points: (i) the lack of a mechanistic explanation for climate-selection relationships, (ii) the appropriateness of the climate data used in our analysis, and (iii) our focus on estimating climate-selection relationships across (rather than within) taxonomic groups. We address these critiques in our response.Supported by NSF grant DEB1620046 (A.M.S.).application/pdfen-AU© The Authors, some rights reserved; exclusive licensee American Association for the Advancement of ScienceResponse to Comment on "Precipitation drives global variation in natural selection"201810.1126/science.aan57602019-05-05