Greenwood, Julian R.Williams, Simon J.2025-06-112025-06-111931-3128PubMed:36521441ORCID:/0000-0003-4781-6261/work/163786710http://www.scopus.com/inward/record.url?scp=85143650678&partnerID=8YFLogxKhttps://hdl.handle.net/1885/733758337BAK1 is a central regulator of extracellular receptor proteins, essential in plant development and defense. In this issue of Cell Host & Microbe, dual reports (Schultze et al. and Yang et al.) describe how intracellular NLR immune receptors guard BAK1, with implications for extracellular perception and immune receptor engineering.S.J.W. is supported by an Australian Research Council (ARC) Future Fellowship ( FT200100135 ) and by the Australian National University Future Scheme ( 35665 ).enPublisher Copyright: © 2022 Elsevier Inc.Guarding the central regulator of extracellular perception in plants – A job for two2022-12-1410.1016/j.chom.2022.11.00885143650678