Lehane, AdeleMarchetti, RosaSpry, ChristinaVan Schalkwyk, DonellyTeng, RongweiKirk, KiaranSaliba, Kevin2015-12-080021-9258http://hdl.handle.net/1885/32459To survive, the human malaria parasite Plasmodium falciparum must acquire pantothenate (vitamin B5) from the external medium. Pantothenol (provitamin B5) inhibits parasite growth by competing with pantothenate for pantothenate kinase, the first enzyme inKeywords: Alcohols; Biosynthesis; Cell culture; Diseases; Microorganisms; Vitamins; Erythrocyte; Pantothenate; Pantothenate kinase; Pantothenol; Enzyme inhibition; coenzyme A; dexpanthenol; furosemide; pantothenate kinase; article; enzyme synthesis; erythrocyte; neFeedback Inhibition of Pantothenate Kinase Regulates Pantothenol Uptake by the Malaria Parasite200710.1074/jbc.M7046102002015-12-08